The Epigenome and Developmental Origins of Health and Disease
  • Publisher : Academic Press
  • Release : 10 October 2015
  • ISBN : 9780128016725
  • Page : 560 pages
  • Rating : /5 from voters

Download or read online book entitled The Epigenome and Developmental Origins of Health and Disease, was written by Cheryl S Rosenfeld and published by Academic Press in pdf, epub and kindle format. This book was released on 10 October 2015 with total pages 560. The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field


Epigenetics Author: Benedikt Hallgrimsson Ph.D.,Brian K. Hall Ph.D.
Publisher: Univ of California Press
Relase: 2011-04-11
ISBN: 9780520948822