Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies
  • Publisher : Academic Press
  • Release : 25 June 2021
  • ISBN : 9780128215685
  • Page : 828 pages
  • Rating : /5 from voters
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Download or read online book entitled Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies, was written by Ramasamy Paulmurugan and published by Academic Press in pdf, epub and kindle format. This book was released on 25 June 2021 with total pages 828. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance