Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance
  • Publisher : Academic Press
  • Release : 04 December 2020
  • ISBN : 9780128213117
  • Page : 308 pages
  • Rating : /5 from voters
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Download or read online book entitled Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, was written by Andrew Freywald and published by Academic Press in pdf, epub and kindle format. This book was released on 04 December 2020 with total pages 308. Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges. Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies


Globalization Biosecurity and the Future of the Life Sciences

Globalization  Biosecurity  and the Future of the Life Sciences Author: National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
Publisher: National Academies Press
Relase: 2006-06-07
ISBN: 0309164753
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